Beta Synuclein (SNCB) (NM_001001502) Human Recombinant Protein

• Background:

  This gene encodes a member of a small family of proteins that inhibit phospholipase D2 and may function in neuronal plasticity. The encoded protein is abundant in lesions of patients with Alzheimer disease. A mutation in this gene was found in individuals with dementia with Lewy bodies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

• Synonyms:

  Beta-synuclein; synuclein, beta

• Gene ID:

  6620

• UniProt:

  Q16143

• Accession Number mRNA:

  NM_001001502

• Chromosomal Location:

  5q35.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  14.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  SNCB

• Species:

  Human

• Protein ID:

  NP_001001502

• Overview:

  Recombinant protein of human synuclein, beta (SNCB), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/6620

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q16143

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001001502

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001001502