PSD95 (DLG4) (NM_001365) Human Recombinant Protein

• Background:

  This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Synonyms:

  MRD62; PSD95; SAP-90; SAP90

• Gene ID:

  1742

• UniProt:

  P78352, B9EGL1, B7Z647

• Accession Number mRNA:

  NM_001365

• Chromosomal Location:

  17p13.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Huntington's disease

• Field of Research:

  Huntington's disease

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  85.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  DLG4

• Species:

  Human

• Protein ID:

  NP_001356

• Overview:

  Recombinant protein of human discs, large homolog 4 (Drosophila) (DLG4), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/1742

• Uniprot URL:

  https://www.uniprot.org/uniprot/P78352

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001365

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001356