RGS11 (NM_183337) Human Recombinant Protein

• Background:

  The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2013]

• Synonyms:

  RS11

• Gene ID:

  8786

• UniProt:

  O94810, Q4TT70

• Accession Number mRNA:

  NM_183337

• Chromosomal Location:

  16p13.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  52.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  RGS11

• Species:

  Human

• Protein ID:

  NP_899180

• Overview:

  Recombinant protein of human regulator of G-protein signaling 11 (RGS11), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/8786

• Uniprot URL:

  https://www.uniprot.org/uniprot/O94810

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_183337

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_899180