AP2B1 (NM_001282) Human Recombinant Protein

• Background:

  The protein encoded by this gene is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Synonyms:

  ADTB2; AP2-BETA; AP105B; CLAPB1

• Gene ID:

  163

• UniProt:

  P63010

• Accession Number mRNA:

  NM_001282

• Chromosomal Location:

  17q12

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Endocytosis, Huntington's disease

• Field of Research:

  Endocytosis, Huntington's disease

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  104.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  AP2B1

• Species:

  Human

• Protein ID:

  NP_001273

• Overview:

  Recombinant protein of human adaptor-related protein complex 2, beta 1 subunit (AP2B1), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/163

• Uniprot URL:

  https://www.uniprot.org/uniprot/P63010

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001282

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001273