IRF5 (NM_001098631) Human Recombinant Protein

• Background:

  This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative promoter use and alternative splicing result in multiple transcript variants, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. [provided by RefSeq, Dec 2016]

• Synonyms:

  Interferon regulatory factor 5; SLEB10

• Gene ID:

  3663

• UniProt:

  Q13568

• Accession Number mRNA:

  NM_001098631

• Chromosomal Location:

  7q32.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Toll-like receptor signaling pathway

• Field of Research:

  Toll-like receptor signaling pathway

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Transcription Factors

• Molecular Weight:

  54.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  IRF5

• Species:

  Human

• Protein ID:

  NP_001092101

• Overview:

  Purified recombinant protein of Homo sapiens interferon regulatory factor 5 (IRF5), transcript variant 7

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/3663

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q13568

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001098631

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001092101