RAPH1 (NM_203365) Human Recombinant Protein

• Background:

  This gene encodes a protein that belongs to the Mig10/Rap1-interacting adaptor molecule/Lamellipodin family of adapter proteins, which function in cell migration. Members of this family contain pleckstrin-homology domains, Ras-association domains, and proline-rich C-termini. The protein encoded by this gene regulates actin dynamics through interaction with Ena/Vasodilator proteins as well as direct binding to filamentous actin to regulate actin network assembly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]

• Synonyms:

  ALS2CR9; ALS2CR18; LPD; PREL-2; PREL2; RalGDS/AF-6; RMO1

• Gene ID:

  65059

• UniProt:

  Q70E73

• Accession Number mRNA:

  NM_203365

• Chromosomal Location:

  2q33.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  72.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  RAPH1

• Species:

  Human

• Protein ID:

  NP_976241

• Overview:

  Recombinant protein of human Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 (RAPH1), transcript variant 3

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/65059

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q70E73

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_203365

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_976241