HIP1R (NM_003959) Human Recombinant Protein

• Background:

  Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain) . May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  HIP3; HIP12; ILWEQ

• Gene ID:

  9026

• UniProt:

  O75146

• Accession Number mRNA:

  NM_003959

• Chromosomal Location:

  12q24.31

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  119.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  HIP1R

• Species:

  Human

• Protein ID:

  NP_003950

• Overview:

  Recombinant protein of human huntingtin interacting protein 1 related (HIP1R)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/9026

• Uniprot URL:

  https://www.uniprot.org/uniprot/O75146

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_003959

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_003950