MAP2 (NM_002374) Human Recombinant Protein

• Background:

  This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010]

• Synonyms:

  MAP-2; MAP2A; MAP2B; MAP2C

• Gene ID:

  4133

• UniProt:

  P11137, Q6NYC5

• Accession Number mRNA:

  NM_002374

• Chromosomal Location:

  2q34

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS

• Molecular Weight:

  199.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  MAP2

• Species:

  Human

• Protein ID:

  NP_002365

• Overview:

  Recombinant protein of human microtubule-associated protein 2 (MAP2), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/4133

• Uniprot URL:

  https://www.uniprot.org/uniprot/P11137

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_002374

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_002365