Neogenin (NEO1) (NM_002499) Human Recombinant Protein

• Background:

  This gene encodes a cell surface protein that is a member of the immunoglobulin superfamily. The encoded protein consists of four N-terminal immunoglobulin-like domains, six fibronectin type III domains, a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC. This protein may be involved in cell growth and differentiation and in cell-cell adhesion. Defects in this gene are associated with cell proliferation in certain cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

• Synonyms:

  IGDCC2; NGN; NTN1R2

• Gene ID:

  4756

• UniProt:

  Q92859, Q59FP8

• Accession Number mRNA:

  NM_002499

• Chromosomal Location:

  15q24.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Cell adhesion molecules (CAMs)

• Field of Research:

  Cell adhesion molecules (CAMs)

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Transmembrane

• Molecular Weight:

  156.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  NEO1

• Species:

  Human

• Protein ID:

  NP_002490

• Overview:

  Recombinant protein of human neogenin homolog 1 (chicken) (NEO1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/4756

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q92859

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_002499

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_002490