SKAP55 (SKAP1) (NM_003726) Human Recombinant Protein

• Background:

  This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. [provided by RefSeq, Jul 2008]

• Synonyms:

  HEL-S-81p; SCAP1; SKAP55

• Gene ID:

  8631

• UniProt:

  Q86WV1

• Accession Number mRNA:

  NM_003726

• Chromosomal Location:

  17q21.32

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  41.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  SKAP1

• Species:

  Human

• Protein ID:

  NP_003717

• Overview:

  Recombinant protein of human src kinase associated phosphoprotein 1 (SKAP1), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/8631

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q86WV1

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_003726

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_003717