MAP4K3 (NM_003618) Human Recombinant Protein

• Background:

  This gene encodes a member of the mitogen-activated protein kinase kinase kinase kinase family. The encoded protein activates key effectors in cell signalling, among them c-Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

• Synonyms:

  GLK; MAPKKKK3; MEKKK 3; MEKKK3; RAB8IPL1

• Gene ID:

  8491

• UniProt:

  Q8IVH8, B3KMM5, A8K602

• Accession Number mRNA:

  NM_003618

• Chromosomal Location:

  2p22.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  MAPK signaling pathway

• Field of Research:

  MAPK signaling pathway

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Protein Kinase

• Molecular Weight:

  101.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  MAP4K3

• Species:

  Human

• Protein ID:

  NP_003609

• Overview:

  Recombinant protein of human mitogen-activated protein kinase kinase kinase kinase 3 (MAP4K3)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/8491

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8IVH8

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_003618

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_003609