L2HGDH (NM_024884) Human Recombinant Protein

• Background:

  This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe cognitive disability. [provided by RefSeq, Jul 2008]

• Synonyms:

  C14orf160; L2HGA

• Gene ID:

  79944

• UniProt:

  Q9H9P8

• Accession Number mRNA:

  NM_024884

• Chromosomal Location:

  14q21.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Butanoate metabolism

• Field of Research:

  Butanoate metabolism

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  45.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  L2HGDH

• Species:

  Human

• Protein ID:

  NP_079160

• Overview:

  Recombinant protein of human L-2-hydroxyglutarate dehydrogenase (L2HGDH), nuclear gene encoding mitochondrial protein

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/79944

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9H9P8

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_024884

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_079160