SIAT4A (ST3GAL1) (NM_003033) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet. [provided by RefSeq, Jul 2008]

• Synonyms:

  1; Gal-NAc6S; SIAT4A; SIATFL; ST3GalA; ST3GalA.1; ST3GalIA; ST3O

• Gene ID:

  6482

• UniProt:

  Q11201, A0A024R9L6

• Accession Number mRNA:

  NM_003033

• Chromosomal Location:

  8q24.22

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Glycosphingolipid biosynthesis - ganglio series, Glycosphingolipid biosynthesis - globo series, Keratan sulfate biosynthesis, Metabolic pathways, O-Glycan biosynthesis

• Field of Research:

  Glycosphingolipid biosynthesis - ganglio series, Glycosphingolipid biosynthesis - globo series, Keratan sulfate biosynthesis, Metabolic pathways, O-Glycan biosynthesis

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Secreted Protein, Transmembrane

• Molecular Weight:

  38.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  ST3GAL1

• Species:

  Human

• Protein ID:

  NP_003024

• Overview:

  Recombinant protein of human ST3 beta-galactoside alpha-2, 3-sialyltransferase 1 (ST3GAL1), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/6482

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q11201

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_003033

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_003024