PTP4A3 (NM_007079) Human Recombinant Protein

• Background:

  This gene encodes a member of the protein-tyrosine phosphatase family. Protein tyrosine phosphatases are cell signaling molecules that play regulatory roles in a variety of cellular processes. Studies of this class of protein tyrosine phosphatase in mice demonstrates that they are prenylated in vivo, suggesting their association with cell plasma membrane. The encoded protein may enhance cell proliferation, and overexpression of this gene has been implicated in tumor metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

• Synonyms:

  PRL-3; PRL-R; PRL3

• Gene ID:

  11156

• UniProt:

  O75365

• Accession Number mRNA:

  NM_007079

• Chromosomal Location:

  8q24.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Phosphatase

• Molecular Weight:

  16.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  PTP4A3

• Species:

  Human

• Protein ID:

  NP_009010

• Overview:

  Recombinant protein of human protein tyrosine phosphatase type IVA, member 3 (PTP4A3), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/11156

• Uniprot URL:

  https://www.uniprot.org/uniprot/O75365

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_007079

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_009010