OSGIN1 (NM_013370) Human Recombinant Protein

• Background:

  This gene encodes an oxidative stress response protein that regulates cell death. Expression of the gene is regulated by p53 and is induced by DNA damage. The protein regulates apoptosis by inducing cytochrome c release from mitochondria. It also appears to be a key regulator of both inflammatory and anti-inflammatory molecules. The loss of this protein correlates with uncontrolled cell growth and tumor formation. Naturally occurring read-through transcription exists between this gene and the neighboring upstream malonyl-CoA decarboxylase (MLYCD) gene, but the read-through transcripts are unlikely to produce a protein product. [provided by RefSeq, Aug 2011]

• Synonyms:

  BDGI; OKL38

• Gene ID:

  29948

• UniProt:

  Q9UJX0

• Accession Number mRNA:

  NM_013370

• Chromosomal Location:

  16q23.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  60.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  OSGIN1

• Species:

  Human

• Protein ID:

  NP_037502

• Overview:

  Recombinant protein of human oxidative stress induced growth inhibitor 1 (OSGIN1), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/29948

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9UJX0

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_013370

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_037502