TNFAIP8L3 (NM_207381) Human Recombinant Protein

• Background:

  Acts as a lipid transfer protein. Preferentially captures and shuttles two lipid second messengers, i.e., phosphatidylinositol 4,5- bisphosphate and phosphatidylinositol 3,4,5-trisphosphate and increases their levels in the plasma membrane. Additionally, may also function as a lipid-presenting protein to enhance the activity of the PI3K-AKT and MEK-ERK pathways. May act as a regulator of tumorigenesis through its activation of phospholipid signaling.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  TIPE3

• Gene ID:

  388121

• UniProt:

  Q5GJ75

• Accession Number mRNA:

  NM_207381

• Chromosomal Location:

  15q21.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  32.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  TNFAIP8L3

• Species:

  Human

• Protein ID:

  NP_997264

• Overview:

  Recombinant protein of human tumor necrosis factor, alpha-induced protein 8-like 3 (TNFAIP8L3)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/388121

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q5GJ75

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_207381

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_997264