INMT (NM_006774) Human Recombinant Protein

• Background:

  N-methylation of endogenous and xenobiotic compounds is a major method by which they are degraded. This gene encodes an enzyme that N-methylates indoles such as tryptamine. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream MINDY4 (aka FAM188B) gene. In rodents and other mammals such as cetartiodactyla this gene is in the opposite orientation compared to its orientation in human and other primates and this gene appears to have been lost in carnivora and chiroptera. [provided by RefSeq, Jul 2019]

• Synonyms:

  TEMT

• Gene ID:

  11185

• UniProt:

  O95050

• Accession Number mRNA:

  NM_006774

• Chromosomal Location:

  7p14.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Tryptophan metabolism

• Field of Research:

  Tryptophan metabolism

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  28.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  INMT

• Species:

  Human

• Protein ID:

  NP_006765

• Overview:

  Recombinant protein of human indolethylamine N-methyltransferase (INMT)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/11185

• Uniprot URL:

  https://www.uniprot.org/uniprot/O95050

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_006774

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_006765