Collagen VI (COL6A2) (NM_058174) Human Recombinant Protein

• Background:

  This gene encodes one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The product of this gene contains several domains similar to von Willebrand Factor type A domains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in this gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene. [provided by RefSeq, Jul 2008]

• Synonyms:

  BTHLM1; PP3610; UCMD1

• Gene ID:

  1292

• UniProt:

  P12110

• Accession Number mRNA:

  NM_058174

• Chromosomal Location:

  21q22.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  ECM-receptor interaction, Focal adhesion

• Field of Research:

  ECM-receptor interaction, Focal adhesion

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Secreted Protein

• Molecular Weight:

  95.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  COL6A2

• Species:

  Human

• Protein ID:

  NP_478054

• Overview:

  Recombinant protein of human collagen, type VI, alpha 2 (COL6A2), transcript variant 2C2a

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/1292

• Uniprot URL:

  https://www.uniprot.org/uniprot/P12110

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_058174

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_478054