Syntenin 2 (SDCBP2) (NM_015685) Human Recombinant Protein

• Background:

  The protein encoded by this gene contains two class II PDZ domains. PDZ domains facilitate protein-protein interactions by binding to the cytoplasmic C-terminus of transmembrane proteins, and PDZ-containing proteins mediate cell signaling and the organization of protein complexes. The encoded protein binds to phosphatidylinositol 4, 5-bisphosphate (PIP2) and plays a role in nuclear PIP2 organization and cell division. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Read-through transcription also exists between this gene and the upstream FKBP1A (FK506 binding protein 1A, 12kDa) gene, as represented in GeneID:100528031. [provided by RefSeq, Sep 2011]

• Synonyms:

  SITAC; SITAC18; ST-2; ST2

• Gene ID:

  27111

• UniProt:

  Q9H190

• Accession Number mRNA:

  NM_015685

• Chromosomal Location:

  20p13

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  22.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  SDCBP2

• Species:

  Human

• Protein ID:

  NP_056500

• Overview:

  Recombinant protein of human syndecan binding protein (syntenin) 2 (SDCBP2), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/27111

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9H190

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_015685

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_056500