TOM1L2 (NM_001082968) Human Recombinant Protein

• Background:

  This gene belongs to a small gene family whose members have an N-terminal VHS domain followed by a GAT domain; domains which typically participate in vesicular trafficking. The canonical protein encoded by this gene also has a C-terminal clathrin binding motif. This protein has been shown to interact with Tollip, clathrin and ubiquitin and is thought to play a role in endosomal sorting. This gene resides in the 3.7 Mb deletion of chromosome region 17p11.2 that is associated with Smith-Magenis syndrome. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Apr 2017]

• Synonyms:

  FLJ21501; FLJ32746

• Gene ID:

  146691

• UniProt:

  Q6ZVM7

• Accession Number mRNA:

  NM_001082968

• Chromosomal Location:

  17p11.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  55.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  TOM1L2

• Species:

  Human

• Protein ID:

  NP_001076437

• Overview:

  Recombinant protein of human target of myb1-like 2 (chicken) (TOM1L2), transcript variant 3

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/146691

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q6ZVM7

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001082968

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001076437