FLCN (NM_144997) Human Recombinant Protein

• Background:

  This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

• Synonyms:

  BHD; DENND8B; FLCL

• Gene ID:

  201163

• UniProt:

  Q8NFG4

• Accession Number mRNA:

  NM_144997

• Chromosomal Location:

  17p11.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Renal cell carcinoma

• Field of Research:

  Renal cell carcinoma

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  64.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  FLCN

• Species:

  Human

• Protein ID:

  NP_659434

• Overview:

  Recombinant protein of human folliculin (FLCN), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/201163

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8NFG4

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_144997

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_659434