EXOC7 (NM_015219) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a component of the exocyst complex. The exocyst complex plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. The encoded protein is required for assembly of the exocyst complex and docking of the complex to the plasma membrane. The encoded protein may also play a role in pre-mRNA splicing through interactions with pre-mRNA-processing factor 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Nov 2011]

• Synonyms:

  2-5-3p; BLOM4; EX070; EXO70; Exo70p; EXOC1; NEDSEBA; YJL085W

• Gene ID:

  23265

• UniProt:

  Q9UPT5, Q63HP7, Q9UPT5-2

• Accession Number mRNA:

  NM_015219

• Chromosomal Location:

  17q25.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Insulin signaling pathway

• Field of Research:

  Insulin signaling pathway

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  74.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  EXOC7

• Species:

  Human

• Protein ID:

  NP_056034

• Overview:

  Recombinant protein of human exocyst complex component 7 (EXOC7), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/23265

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9UPT5

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_015219

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_056034