USP15 (NM_006313) Human Recombinant Protein

• Background:

  This gene encodes a member of the ubiquitin specific protease (USP) family of deubiquitinating enzymes. USP enzymes play critical roles in ubiquitin-dependent processes through polyubiquitin chain disassembly and hydrolysis of ubiquitin-substrate bonds. The encoded protein associates with the COP9 signalosome, and also plays a role in transforming growth factor beta signalling through deubiquitination of receptor-activated SMAD transcription factors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 2. [provided by RefSeq, Nov 2011]

• Synonyms:

  UNPH-2; UNPH4

• Gene ID:

  9958

• UniProt:

  Q9Y4E8

• Accession Number mRNA:

  NM_006313

• Chromosomal Location:

  12q14.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Protease

• Molecular Weight:

  109.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  USP15

• Species:

  Human

• Protein ID:

  NP_006304

• Overview:

  Recombinant protein of human ubiquitin specific peptidase 15 (USP15)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/9958

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9Y4E8

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_006313

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_006304