H2BU1 (NM_175055) Human Recombinant Protein

• Background:

  Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Aug 2015]

• Synonyms:

  H2Bb; HIST3H2BB

• Gene ID:

  128312

• UniProt:

  Q8N257

• Accession Number mRNA:

  NM_175055

• Chromosomal Location:

  1q42.13

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Systemic lupus erythematosus

• Field of Research:

  Systemic lupus erythematosus

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  13.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  H2BU1

• Species:

  Human

• Protein ID:

  NP_778225

• Overview:

  Recombinant protein of human histone cluster 3, H2bb (HIST3H2BB)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/128312

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8N257

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_175055

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_778225