Beta Casein (CSN2) (NM_001891) Human Recombinant Protein

• Background:

  This gene is a member of the beta casein family. There are two types of casein protein, beta (encoded by this gene) and kappa, both of which are secreted in human milk. Beta casein is the principal protein in human milk and the primary source of essential amino acids for a suckling infant. Beta and kappa casein proteins acting together form spherical micelles which bind within them important dietary minerals, such as calcium and phosphorous. In addition, the C-terminal 14 aa of the protein has antimicrobial activity, especially in preterm milk, displaying antibacterial activity against S. aureus and Y. enterocolitica. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2020]

• Synonyms:

  CASB; PDC213

• Gene ID:

  1447

• UniProt:

  P05814, W5RWE1

• Accession Number mRNA:

  NM_001891

• Chromosomal Location:

  4q13.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Secreted Protein

• Molecular Weight:

  25.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CSN2

• Species:

  Human

• Protein ID:

  NP_001882

• Overview:

  Recombinant protein of human casein beta (CSN2)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/1447

• Uniprot URL:

  https://www.uniprot.org/uniprot/P05814

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001891

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001882