Alpha Adducin (ADD1) (NM_001119) Human Recombinant Protein

• Background:

  Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma) . Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca (2+) /calmodulin and is a substrate for protein kinases A and C. [provided by RefSeq, Aug 2017]

• Synonyms:

  ADDA

• Gene ID:

  118

• UniProt:

  P35611

• Accession Number mRNA:

  NM_001119

• Chromosomal Location:

  4p16.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  80.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  ADD1

• Species:

  Human

• Protein ID:

  NP_001110

• Overview:

  Recombinant protein of human adducin 1 (alpha) (ADD1), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/118

• Uniprot URL:

  https://www.uniprot.org/uniprot/P35611

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001119

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001110