POU6F2 (NM_007252) Human Recombinant Protein

• Background:

  This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Oct 2009]

• Synonyms:

  RPF-1; WT5; WTSL

• Gene ID:

  11281

• UniProt:

  P78424

• Accession Number mRNA:

  NM_007252

• Chromosomal Location:

  7p14.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Transcription Factors

• Molecular Weight:

  73.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  POU6F2

• Species:

  Human

• Protein ID:

  NP_009183

• Overview:

  Recombinant protein of human POU class 6 homeobox 2 (POU6F2)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/11281

• Uniprot URL:

  https://www.uniprot.org/uniprot/P78424

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_007252

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_009183