ADH7 (NM_000673) Human Recombinant Protein

• Background:

  This gene encodes class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The enzyme encoded by this gene is inefficient in ethanol oxidation, but is the most active as a retinol dehydrogenase; thus it may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. The expression of this gene is much more abundant in stomach than liver, thus differing from the other known gene family members. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

• Synonyms:

  ADH4

• Gene ID:

  131

• UniProt:

  P40394

• Accession Number mRNA:

  NM_000673

• Chromosomal Location:

  4q23

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Drug metabolism - cytochrome P450, Fatty acid metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism, Tyrosine metabolism

• Field of Research:

  Drug metabolism - cytochrome P450, Fatty acid metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism, Tyrosine metabolism

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  41.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  ADH7

• Species:

  Human

• Protein ID:

  NP_000664

• Overview:

  Recombinant protein of human alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide (ADH7)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/131

• Uniprot URL:

  https://www.uniprot.org/uniprot/P40394

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_000673

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_000664