KGF (FGF7) (NM_002009) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis. [provided by RefSeq, Jul 2008]

• Synonyms:

  HBGF-7; KGF

• Gene ID:

  2252

• UniProt:

  P21781

• Accession Number mRNA:

  NM_002009

• Chromosomal Location:

  15q21.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

• Field of Research:

  MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Secreted Protein

• Molecular Weight:

  18.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  FGF7

• Species:

  Human

• Protein ID:

  NP_002000

• Overview:

  Recombinant protein of human fibroblast growth factor 7 (keratinocyte growth factor) (FGF7)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/2252

• Uniprot URL:

  https://www.uniprot.org/uniprot/P21781

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_002009

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_002000