MECR (NM_016011) Human Recombinant Protein

• Background:

  The protein encoded by this gene is an oxidoreductase that catalyzes the last step in mitochondrial fatty acid synthesis. Defects in this gene are a cause of childhood-onset dystonia and optic atrophy. [provided by RefSeq, Mar 2017]

• Synonyms:

  CGI-63; DYTOABG; ETR1; FASN2B; NRBF1

• Gene ID:

  51102

• UniProt:

  Q9BV79

• Accession Number mRNA:

  NM_016011

• Chromosomal Location:

  1p35.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Fatty acid elongation in mitochondria, Metabolic pathways

• Field of Research:

  Fatty acid elongation in mitochondria, Metabolic pathways

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  40.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  MECR

• Species:

  Human

• Protein ID:

  NP_057095

• Overview:

  Recombinant protein of human mitochondrial trans-2-enoyl-CoA reductase (MECR), nuclear gene encoding mitochondrial protein, transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/51102

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9BV79

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_016011

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_057095