MACC1 (NM_182762) Human Recombinant Protein

• Background:

  MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409) -HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]) .[supplied by OMIM, Mar 2009]

• Synonyms:

  7A5; SH3BP4L

• Gene ID:

  346389

• UniProt:

  Q6ZN28

• Accession Number mRNA:

  NM_182762

• Chromosomal Location:

  7p21.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  96.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  MACC1

• Species:

  Human

• Protein ID:

  NP_877439

• Overview:

  Recombinant protein of human metastasis associated in colon cancer 1 (MACC1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/346389

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q6ZN28

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_182762

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_877439