SH2B1 (NM_001145795) Human Recombinant Protein

• Background:

  This gene encodes a member of the SH2-domain containing mediators family. The encoded protein mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]

• Synonyms:

  PSM; SH2B

• Gene ID:

  25970

• UniProt:

  Q9NRF2, A0A024QZD2, B4DLN5, B3KNV5

• Accession Number mRNA:

  NM_001145795

• Chromosomal Location:

  16p11.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Neurotrophin signaling pathway

• Field of Research:

  Neurotrophin signaling pathway

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  79.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  SH2B1

• Species:

  Human

• Protein ID:

  NP_001139267

• Overview:

  Recombinant protein of human SH2B adaptor protein 1 (SH2B1), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/25970

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9NRF2

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001145795

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001139267