CITED2 (NM_001168388) Human Recombinant Protein

• Background:

  The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of hypoxia-inducible factor 1-alpha to p300-CH1. Mutations in this gene are a cause of cardiac septal defects. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]

• Synonyms:

  ASD8; MRG-1; MRG1; P35SRJ; VSD2

• Gene ID:

  10370

• UniProt:

  Q99967, D9ZGF1

• Accession Number mRNA:

  NM_001168388

• Chromosomal Location:

  6q24.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Transcription Factors

• Molecular Weight:

  28.9

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CITED2

• Species:

  Human

• Protein ID:

  NP_001161860

• Overview:

  Purified recombinant protein of Homo sapiens Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 (CITED2), transcript variant 2.

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/10370

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q99967

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001168388

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001161860