ASB2 (NM_016150) Human Recombinant Protein

• Background:

  This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

• Synonyms:

  ASB-2

• Gene ID:

  51676

• UniProt:

  Q96Q27

• Accession Number mRNA:

  NM_016150

• Chromosomal Location:

  14q32.12

• Expression System:

  E. coli

• Tag:

  N-His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  50mM Tris, 8M Urea, pH8.0.

• Function:

  Druggable Genome

• Molecular Weight:

  32.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  ASB2

• Species:

  Human

• Protein ID:

  NP_057234

• Overview:

  Purified recombinant protein of Human ankyrin repeat and SOCS box containing 2 (ASB2), transcript variant 2, Met1-Gly300, with N-terminal His tag, expressed in E.coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/51676

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q96Q27

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_016150

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_057234