Complement Component 6 (C6) (NM_000065) Human Recombinant Protein

• Background:

  This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.[provided by RefSeq, Nov 2012]

• Synonyms:

  Complement component 6; OTTHUMP00000120010

• Gene ID:

  729

• UniProt:

  P13671

• Accession Number mRNA:

  NM_000065

• Chromosomal Location:

  5p13.1

• Expression System:

  E. coli

• Tag:

  N-His

• Related Pathways:

  Complement and coagulation cascades, Prion diseases, Systemic lupus erythematosus

• Field of Research:

  Complement and coagulation cascades, Prion diseases, Systemic lupus erythematosus

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  50mM Tris, 8M Urea, pH8.0.

• Function:

  Druggable Genome, Secreted Protein

• Molecular Weight:

  38.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  C6

• Species:

  Human

• Protein ID:

  NP_000056

• Overview:

  Purified recombinant protein of Human complement component 6 (C6), transcript variant 1, Thr176-Gln522, with N-terminal His tag, expressed in E.coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/729

• Uniprot URL:

  https://www.uniprot.org/uniprot/P13671

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_000065

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_000056