SARA (ZFYVE9) (NM_004799) Human Recombinant Protein

• Background:

  This gene encodes a double zinc finger motif-containing protein that participates in the transforming growth factor-beta (TGFB) signalling pathway. The encoded protein interacts directly with SMAD2 and SMAD3, and recruits SMAD2 to the TGFB receptor. There are multiple pseudogenes for this gene on chromosomes 2, 15, and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]

• Synonyms:

  MADHIP; NSP; PPP1R173; SARA; SMADIP

• Gene ID:

  9372

• UniProt:

  O95405

• Accession Number mRNA:

  NM_004799

• Chromosomal Location:

  1p32.3

• Expression System:

  E. coli

• Tag:

  N-His

• Related Pathways:

  TGF-beta signaling pathway

• Field of Research:

  TGF-beta signaling pathway

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  50mM Tris, 8M Urea, pH8.0.

• Molecular Weight:

  21.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  ZFYVE9

• Species:

  Human

• Protein ID:

  NP_004790

• Overview:

  Purified recombinant protein of Human zinc finger, FYVE domain containing 9 (ZFYVE9), transcript variant 3, Asp699-Ile899, with N-terminal His tag, expressed in E.coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/9372

• Uniprot URL:

  https://www.uniprot.org/uniprot/O95405

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_004799

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_004790