VAP1 (AOC3) (NM_003734) Human Recombinant Protein

• Background:

  This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]

• Synonyms:

  HPAO; SSAO; VAP-1; VAP1

• Gene ID:

  8639

• UniProt:

  Q16853, Q9UEU7

• Accession Number mRNA:

  NM_003734

• Chromosomal Location:

  17q21.31

• Expression System:

  E. coli

• Tag:

  N-His

• Related Pathways:

  Beta-Alanine metabolism, Glycine, serine and threonine metabolism, Metabolic pathways, Phenylalanine metabolism, Tyrosine metabolism

• Field of Research:

  Beta-Alanine metabolism, Glycine, serine and threonine metabolism, Metabolic pathways, Phenylalanine metabolism, Tyrosine metabolism

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  50mM Tris, 8M Urea, pH8.0.

• Function:

  Transmembrane

• Molecular Weight:

  25.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  AOC3

• Species:

  Human

• Protein ID:

  NP_003725

• Overview:

  Purified recombinant protein of Human amine oxidase, copper containing 3 (vascular adhesion protein 1) (AOC3), Gly27-Pro256, with N-terminal His tag, expressed in E.coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/8639

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q16853

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_003734

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_003725