Cyclin T2 (CCNT2) (NM_001241) Human Recombinant Protein

• Background:

  The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]

• Synonyms:

  CYCT2

• Gene ID:

  905

• UniProt:

  O60583, B4DH21

• Accession Number mRNA:

  NM_001241

• Chromosomal Location:

  2q21.3

• Expression System:

  E. coli

• Tag:

  N-His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  50mM Tris, 8M Urea, pH8.0.

• Function:

  Druggable Genome, Transcription Factors

• Molecular Weight:

  29.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CCNT2

• Species:

  Human

• Protein ID:

  NP_001232

• Overview:

  Purified recombinant protein of Human cyclin T2 (CCNT2), transcript variant a, Ala7-Ala263, with N-terminal His tag, expressed in E.coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/905

• Uniprot URL:

  https://www.uniprot.org/uniprot/O60583

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001241

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001232