Cyclin G2 (CCNG2) (NM_004354) Human Recombinant Protein

• Background:

  The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved among mammals. The nucleotide sequence of cyclin G1 and cyclin G2 are 53% identical. Unlike cyclin G1, cyclin G2 contains a C-terminal PEST protein destabilization motif, suggesting that cyclin G2 expression is tightly regulated through the cell cycle. [provided by RefSeq, Jul 2008]

• Synonyms:

  Cyclin G2; OTTHUMP00000160592

• Gene ID:

  901

• UniProt:

  Q16589, A0A024RDC7

• Accession Number mRNA:

  NM_004354

• Chromosomal Location:

  4q21.1

• Expression System:

  E. coli

• Tag:

  N-His

• Related Pathways:

  P53 signaling pathway

• Field of Research:

  P53 signaling pathway

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  50mM Tris, 8M Urea, pH8.0.

• Function:

  Druggable Genome

• Molecular Weight:

  38.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CCNG2

• Species:

  Human

• Protein ID:

  NP_004345

• Overview:

  Purified recombinant protein of Human cyclin G2 (CCNG2), full length, with N-terminal His tag, expressed in E.coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/901

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q16589

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_004354

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_004345