NCOA4 (NM_001145260) Human Recombinant Protein

• Background:

  This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14. [provided by RefSeq, Feb 2009]

• Synonyms:

  ARA70; ELE1; PTC3; RFG

• Gene ID:

  8031

• UniProt:

  Q13772, Q96E88

• Accession Number mRNA:

  NM_001145260

• Chromosomal Location:

  10q11.22

• Expression System:

  E. coli

• Tag:

  N-His

• Related Pathways:

  Pathways in cancer, Thyroid cancer

• Field of Research:

  Pathways in cancer, Thyroid cancer

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  >80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  50mM Tris, pH8.0, 8M Urea

• Function:

  Druggable Genome, Transcription Factors

• Molecular Weight:

  31.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  NCOA4

• Species:

  Human

• Protein ID:

  NP_001138732

• Overview:

  Purified recombinant protein of Human nuclear receptor coactivator 4 (NCOA4), transcript variant 1, Ser280-Ala553, with N-terminal His tag, expressed in E.coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/8031

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q13772

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001145260

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001138732