Aurora A (AURKA) (NM_198435) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

• Synonyms:

  AIK; ARK1; AURA; BTAK; PPP1R47; STK6; STK7; STK15

• Gene ID:

  6790

• UniProt:

  O14965

• Accession Number mRNA:

  NM_198435

• Chromosomal Location:

  20q13.2

• Expression System:

  E. coli

• Tag:

  N-His

• Related Pathways:

  Oocyte meiosis

• Field of Research:

  Oocyte meiosis

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  >80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  50mM Tris, pH8.0, 8M Urea

• Function:

  Druggable Genome, Protein Kinase, Stem cell - Pluripotency

• Molecular Weight:

  33.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  AURKA

• Species:

  Human

• Protein ID:

  NP_940837

• Overview:

  Purified recombinant protein of Human aurora kinase A (AURKA), transcript variant 4, Met1-Met300, with N-terminal His tag, expressed in E.coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/6790

• Uniprot URL:

  https://www.uniprot.org/uniprot/O14965

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_198435

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_940837