Eif4ebp3 (NM_201256) Mouse Recombinant Protein

• Background:

  Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  4e-bp3

• Gene ID:

  108112

• UniProt:

  Q80VV3

• Accession Number mRNA:

  NM_201256

• Chromosomal Location:

  18 B2

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  11.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Eif4ebp3

• Species:

  Mouse

• Protein ID:

  NP_957708

• Overview:

  Purified recombinant protein of Mouse eukaryotic translation initiation factor 4E binding protein 3 (Eif4ebp3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/108112

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q80VV3

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_201256

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_957708