Apomorphine

• Product Name Alternative:

  (-)-Apomorphine

• UNSPSC Description:

  Apomorphine is an orally active agonist of Dopamine receptor. Apomorphine can be used in study Parkinson, biphasic dyskinesias, urinary dysfunction,,dystonia, dyspnoea, anismus and belching[1].

• Target Antigen:

  5-HT Receptor; Dopamine Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/apomorphine.html

• Purity:

  99.48

• Solubility:

  DMSO : 26 mg/mL (ultrasonic;warming)

• Smiles:

  OC1=CC=C2C(C3=C4C(CCN(C)[C@]4([H])C2)=CC=C3)=C1O

• Molecular Weight:

  267.32

• References & Citations:

  [1]Frankel JP, et al. Subcutaneous apomorphine in the treatment of Parkinson's disease. J Neurol Neurosurg Psychiatry. 1990 Feb;53(2):96-101.|[2]Carbone F, et al. Apomorphine for Parkinson's Disease: Efficacy and Safety of Current and New Formulations. CNS Drugs. 2019 Sep;33(9):905-918.Funct Integr Genomics. 2024 Sep 17;24(5):161.|Andrologia. 2019 Feb;51(1):e13160.|Andrology. 2022 Mar 2.|Asian J Androl. 2018 Sep-Oct;20(5):448-453.|J Sex Med. 2018 Feb;15(2):136-147. |Oxid Med Cell Longev. 2018 Jun 26;2018:2917981. |Sci Rep. 2019 Jan 22;9(1):254.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  Launched

• CAS Number:

  58-00-4