Apomorphine

• Description :

  Apomorphine is an orally active agonist of Dopamine receptor. Apomorphine can be used in study Parkinson, biphasic dyskinesias, urinary dysfunction, , dystonia, dyspnoea, anismus and belching[1].

• Product Name Alternative :

  (-) -Apomorphine

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H312, H332

• Target :

  5-HT Receptor; Dopamine Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neurodegeneration

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/apomorphine.html

• Purity :

  99.48

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  OC1=CC=C2C(C3=C4C(CCN(C)[C@]4([H])C2)=CC=C3)=C1O

• Molecular Formula :

  C17H17NO2

• Molecular Weight :

  267.32

• Precautions :

  H302, H312, H332

• References & Citations :

  [1]Frankel JP, et al. Subcutaneous apomorphine in the treatment of Parkinson's disease. J Neurol Neurosurg Psychiatry. 1990 Feb;53 (2) :96-101.|[2]Carbone F, et al. Apomorphine for Parkinson's Disease: Efficacy and Safety of Current and New Formulations. CNS Drugs. 2019 Sep;33 (9) :905-918.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• Citation 01 :

  Funct Integr Genomics. 2024 Sep 17;24 (5) :161.|Genes. 2025 Jun 29;16 (7) :768.|NPJ Parkinsons Dis. 2025 Nov 28;11 (1) :342.|Acta Pharmacol Sin. 2025 May 6.|Sci Rep. 2019 Jan 22;9 (1) :254. |Andrologia. 2019 Feb;51 (1) :e13160.|Andrology. 2022 May;10 (4) :808-817.|Asian J Androl. 2018 Sep-Oct;20 (5) :448-453.|J Sex Med. 2018 Feb;15 (2) :136-147. |Oxid Med Cell Longev. 2018 Jun 26:2018:2917981.

• CAS Number :

  [58-00-4]