Tprkb (BC027162) Mouse Recombinant Protein

• Background:

  Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t (6) A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t (6) A activity of the complex. TPRKB is not required for tRNA modification.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  Cgi-121, mDRWMS1, DRWMS1

• Gene ID:

  69786

• UniProt:

  Q8QZZ7

• Accession Number mRNA:

  BC027162

• Chromosomal Location:

  6 C3

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  19.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Tprkb

• Species:

  Mouse

• Overview:

  Purified recombinant protein of Mouse Tp53rk binding protein (cDNA clone MGC:37089 IMAGE:4951567), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/69786

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8QZZ7

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/BC027162