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Tprkb (BC027162) Mouse Recombinant Protein

CAT: 0882-PM48600M5Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0882-PM48600M5Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t (6) A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t (6) A activity of the complex. TPRKB is not required for tRNA modification.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse Tp53rk binding protein (cDNA clone MGC:37089 IMAGE:4951567), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
Cgi-121, mDRWMS1, DRWMS1
Gene ID
69786
UniProt
Q8QZZ7
Accession Number mRNA
BC027162
Chromosomal Location
6 C3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
19.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Tprkb
Species
Mouse
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/69786
Uniprot URL
https://www.uniprot.org/uniprot/Q8QZZ7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC027162

UniProtKB · Q8QZZ7

EKC/KEOPS complex subunit Tprkb

TPRKB_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q8QZZ7
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Tprkb
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
—
Processing
—
Secondary accessions
—
Protein keywords

Cellular component

CytoplasmNucleus

Technical term

Reference proteome

Biological process

tRNA processing

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