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Ict1 (BC028523) Mouse Recombinant Protein

CAT: 0882-PM48286M5Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0882-PM48286M5Size:20 µg
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Background
Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit (PubMed:20869366) . Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse immature colon carcinoma transcript 1 (cDNA clone MGC:41300 IMAGE:2938122), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
1110001A02Rik; 1110002E03Rik; MRP-L58
Gene ID
68572
UniProt
Q8R035
Accession Number mRNA
BC028523
Chromosomal Location
11 E2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
23.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Ict1
Species
Mouse
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/68572
Uniprot URL
https://www.uniprot.org/uniprot/Q8R035
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC028523

UniProtKB · Q8R035

Large ribosomal subunit protein mL62

ICT1_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q8R035
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Mrpl58
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A2A6T2, A2A6T3, Q3TUL0, Q9CTK1, Q9D1R3
Protein keywords

Technical term

3D-structureReference proteome

Coding sequence diversity

Alternative splicing

Molecular function

HydrolaseRibonucleoproteinRibosomal protein

PTM

Methylation

Cellular component

Mitochondrion

Biological process

Protein biosynthesis

Domain

Transit peptide

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