Ict1 (BC028523) Mouse Recombinant Protein

• Background:

  Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit (PubMed:20869366) . Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes (By similarity) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  1110001A02Rik; 1110002E03Rik; MRP-L58

• Gene ID:

  68572

• UniProt:

  Q8R035

• Accession Number mRNA:

  BC028523

• Chromosomal Location:

  11 E2

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  23.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Ict1

• Species:

  Mouse

• Overview:

  Purified recombinant protein of Mouse immature colon carcinoma transcript 1 (cDNA clone MGC:41300 IMAGE:2938122), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/68572

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8R035

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/BC028523