Bcl2l1 (NM_009743) Mouse Recombinant Protein

• Background:

  This gene encodes a member of the Bcl-2 family of apoptosis regulators. The encoded protein is localized to the inner and outer mitochondrial membranes and regulates the programmed cell death pathway during development and tissue homeostasis. This protein binds to voltage-dependent anion channels in the outer mitochondrial membrane to facilitate the uptake of calcium ions. Mice embryos lacking this gene survived for two weeks and exhibited cell death of immature hematopoietic cells and neurons. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jan 2014]

• Synonyms:

  Bcl; Bcl (X; Bcl (X) L; bcl-; bcl-x; Bcl-XL; bcl2-L-1; Bcl2l; BclX

• Gene ID:

  12048

• UniProt:

  Q64373, Q5HZH3

• Accession Number mRNA:

  NM_009743

• Chromosomal Location:

  2 H1

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  26.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Bcl2l1

• Species:

  Mouse

• Protein ID:

  NP_033873

• Overview:

  Purified recombinant protein of Mouse BCL2-like 1 (Bcl2l1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/12048

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q64373

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_009743

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_033873