Apip (NM_019735) Mouse Recombinant Protein

• Background:

  Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) . Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  APIP2; CGI-29; Mmrp19

• Gene ID:

  56369

• UniProt:

  Q9WVQ5

• Accession Number mRNA:

  NM_019735

• Chromosomal Location:

  2 E2

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  26.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Apip

• Species:

  Mouse

• Protein ID:

  NP_062709

• Overview:

  Purified recombinant protein of Mouse APAF1 interacting protein (Apip), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/56369

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9WVQ5

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_019735

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_062709