Dnajb6 (NM_001127367) Mouse Recombinant Protein

• Background:

  Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins (By similarity) . Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity (By similarity) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  HSJ-2; mDj4; Mrj

• Gene ID:

  23950

• UniProt:

  O54946

• Accession Number mRNA:

  NM_001127367

• Chromosomal Location:

  5 B1

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  27 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Dnajb6

• Species:

  Mouse

• Protein ID:

  NP_001120839

• Overview:

  Purified recombinant protein of Mouse DnaJ heat shock protein family (Hsp40) member B6 (Dnajb6), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/23950

• Uniprot URL:

  https://www.uniprot.org/uniprot/O54946

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001127367

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001120839