Anp32e (NM_023210) Mouse Recombinant Protein

• Background:

  Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AFZ from the nucleosome: removes H2A.Z/H2AFZ from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AFZ in the nucleosome. May stabilize the evicted H2A.Z/H2AFZ-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state (PubMed:24463511) . Inhibits activity of protein phosphatase 2A (PP2A) . Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  2810018A15Rik; AI047746; AI326868; CPD1; LANP-L; LANPL; mLANP-L

• Gene ID:

  66471

• UniProt:

  P97822

• Accession Number mRNA:

  NM_023210

• Chromosomal Location:

  3 F2.1

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  30.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Anp32e

• Species:

  Mouse

• Protein ID:

  NP_075699

• Overview:

  Purified recombinant protein of Mouse acidic (leucine-rich) nuclear phosphoprotein 32 family, member E (Anp32e), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/66471

• Uniprot URL:

  https://www.uniprot.org/uniprot/P97822

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_023210

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_075699