Itm2b (NM_008410) Mouse Recombinant Protein

• Background:

  Plays a regulatory role in the processing of the amyloid-beta A4 precursor protein (APP) and acts as an inhibitor of the amyloid-beta peptide aggregation and fibrils deposition. Plays a role in the induction of neurite outgrowth. Functions as a protease inhibitor by blocking access of secretases to APP cleavage sites (By similarity) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  AI256040; Bri; Bri2; Bricd2b; D14Sel6; E25BMM; imBRI2

• Gene ID:

  16432

• UniProt:

  O89051

• Accession Number mRNA:

  NM_008410

• Chromosomal Location:

  14 38.88 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  30.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Itm2b

• Species:

  Mouse

• Protein ID:

  NP_032436

• Overview:

  Purified recombinant protein of Mouse integral membrane protein 2B (Itm2b), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/16432

• Uniprot URL:

  https://www.uniprot.org/uniprot/O89051

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_008410

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_032436